Milrinone Lactate
A to Z Drug Facts
Milrinone Lactate |
(MILL-rih-nohn LAK-tate) |
Primacor |
Class: Cardiovascular |
Action Has direct arterial vasodilator activity and positive inotropic effect; ncreases myocardial contractility.
Indications Short-term treatment of CHF.
Contraindications Standard considerations.
ADULTS: IV Loading dose: 50 mcg/kg over 10 min; adjust infusion rate according to hemodynamic and clinical response.
Interactions None well documented. INCOMPATIBILITIES: Precipitate forms if furosemide is injected into same IV line as milrinone; do not administer both in same IV line.
Lab Test Interferences None well documented.
CV: Ventricular arrhythmia (eg, ventricular ectopic activity, nonsustained ventricular tachycardia, sustained ventricular tachycardia, ventricular fibrillation); supraventricular arrhythmia; hypotension; angina. CNS: Headaches; tremor. Thrombocytopenia. OTHER: Hypokalemia.
Pregnancy: Category C. Lactation: Undetermined. Children: Safety and efficacy not established. Cardiovascular effects: Do not use in patients with severe obstructive aortic or pulmonic valvular disease; may exacerbate hypertrophic subaortic stenosis; may cause supraventricular and ventricular arrhythmias; may shorten atrioventricular node conduction. Renal impairment: Use drug with caution; monitor renal function. Dosage reduction, based on creatinine clearance, may be needed.
PATIENT CARE CONSIDERATIONS |
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Copyright © 2003 Facts and Comparisons
David S. Tatro
A to Z Drug Facts